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Course No. 3393.505
Biological
Sequence Analysis |
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Interdisciplinary Bioinformatics Program, Seoul
National University |
| Instructor |
- Prof. Byoung-Tak
Zhang
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| TA: |
- Jang-Min Oh, jmoh@bi.snu.ac.kr, Tel.: 880-1847, Room 301-419 오장민 12월20일부터 4주간 자리 비웁니다. 보고서를 오장민에게 보내지 마세요... 절대로
- 엄재홍, [E-mail addr. was deleted for anti spam], Tel.: 880-1847, Room 301-419 (프로젝트1제출)
- 지성욱, swchi@cbit.snu.ac.kr, Tel.: 880-5890, Room 138-409 (프로젝트2제출)
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-
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| Classroom |
- 18-403
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| Time |
- Wednesday,
9:15-12:00
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- Textbook
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- Biological
Sequence Analysis: Probabilistic
Models of Proteins and Nucleic Acids, Richard
Durbin. S. Eddy, A. Krogh, G. Mitchison.
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- Requirements
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- Two exams: 40 %, two projects: 40%, homeworks: 15%, class participation:
5%
Project 1: Gene finding with probabilistic
models
Project 2: Analysis in
RNA sequences
with probabilistic models |
- Objectives
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- Understanding probabilistic models, particularly
hidden Markov models (HMMs).
- Understanding
analysis of a wide variety of sequence
analysis problems.
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| Date |
Main Subjects
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Week 1
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Introduction (Chap 1) [pdf slids (Slide A: COLOR,
B/W)
(Slide B: COLOR,
B/W)]
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Week 2
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Background on probability (Chap 11) [pdf slids COLOR,
B/W]
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| Week 3 |
Background on probability (Chap 11)
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Week 4
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Pairwise alignment (Chap 2) [pdf slids COLOR,
B/W] |
Week 5
Week 6
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Markov chains and hidden Markov models (Chap 3) [pdf slids
#1 COLOR,
B/W][pdf slids
#2 COLOR,
B/W]
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Week 7
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Assignment
of Project (Project):
HMM
Tutorial, HMMER
Tutorial
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 Click!
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| Week 8 |
Midterm Exam |
Week
9
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Pairwise alignment using HMMs (Chap 4) [ppt slide:
PPT]
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Week
10
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Profile HMMs for sequence families (Chap 5) [ppt slide: PPT] |
Week
11
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Project Midterm Presentations: Schedule |
Week
12
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Multiple sequence alignment
methods (Chap 6)[ppt slide:
PPT]
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Week
13
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Transformational grammars (Chap 9) |
Week
14
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과제 발표
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Week
15
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Final Exam(12월18일)
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보고서제출 마감(12월16일)
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Back to [BI
Lab] [BTZhang's Home Page] [Dept. of Computer
Eng.] | |