Bioinformatics and computational biology in the era of

high-through sequencing

   February 3,  2014, 11AM

302- 308

 

Abstract:

Recent development high-throughput sequencing (HTS) technologies enabled low-cost production of various levels of genome wide mapping information such as protein-DNA interaction, gene expression, epigenetic modification, and so on. Now they are essential tools for studying gene regulation and epigenomic phenomena. Although the number of newly generated data is rapidly increasing, they are yet to be fully utilized and the role of bioinformatics is more demanding. In this talk, starting with the basic concepts of HTS-based data, various examples of their application in metabolism research will be introduced. And finally, as a more detailed story, recent finding in gene regulation by an anti-diabetic drug using a new type HTS data will also be covered